Understanding Spravato: Hope for Treatment Resistant Depression

Noah Warren
September 14, 2023

Depression is a debilitating mental illness that can significantly impact an individual's quality of life. While traditional treatments such as medication and therapy can be effective for some individuals, others continue to experience symptoms, leading to treatment-resistant depression. Thankfully, advances in pharmacology have led to the development of Spravato, a medication approved by the FDA for the treatment of treatment-resistant depression.

In this article, we'll explore what Spravato is, when it was FDA cleared, how insurance works with paying for Spravato, and how it's integrated with psychotherapy in treating depression.

spravato
Source: Med Page Today

Understanding Spravato

Spravato is a nasal spray medication that contains esketamine, a drug that targets the NMDA receptor in the brain. This receptor plays a crucial role in the regulation of mood, and by targeting it, Spravato can alleviate depression symptoms quickly. Spravato is administered under supervision in a healthcare facility, with patients monitored for at least two hours following administration.

FDA Clearance

The FDA approved Spravato in March 2019 for the treatment of treatment-resistant depression. The approval followed extensive clinical trials and data analysis, which demonstrated its efficacy in reducing symptoms of depression, including suicidal ideation.

Insurance Coverage

Insurance coverage for Spravato varies depending on the individual's insurance plan. Some insurance companies require prior authorization, while others may have specific requirements regarding the provider or healthcare facility. It's important to check with your insurance provider to determine coverage and any associated out-of-pocket expenses.

Integration with Psychotherapy

While Spravato can be an effective standalone treatment for depression, it's most effective when used in conjunction with psychotherapy. Therapy can provide a supportive environment for individuals seeking to work through underlying issues contributing to their depression. By integrating Spravato with psychotherapy, individuals can receive comprehensive care tailored to their unique needs.

Efficacy

Clinical trials have demonstrated the efficacy of Spravato in treating treatment-resistant depression. One clinical trial showed that individuals who received Spravato experienced a significant reduction in depression symptoms. Additionally, Spravato has been shown to reduce suicidal ideation in individuals with treatment-resistant depression.

Conclusion

Depression is a complex mental illness that can significantly impact an individual's life. While traditional treatments can be effective for some individuals, others continue to experience symptoms despite treatment. Thanks to advances in pharmacology, Spravato has emerged as a promising option for the treatment of treatment-resistant depression.

By targeting the NMDA receptor in the brain, Spravato can alleviate depression symptoms quickly and effectively. When used in conjunction with psychotherapy, individuals can receive comprehensive care tailored to their unique needs. It's important to determine insurance coverage and any associated out-of-pocket expenses. With continued research and development, we can continue to improve the lives of those struggling with depression and provide hope for a brighter future.

If you are interested in learning more about Spravato, you can schedule a free consultation with a professional at Roots Mental Wellness, and we’ll be happy to answer any of your questions.

Noah Warren
Director of Business Development